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This results in a greater pH change and a proportionally greater electronic signal.[11] This is a limitation of the system in that it is difficult to enumerate long repeats. These are loaded onto the instrument, along with DNA Sequencing Kit 1.0 (Part Number 001-379-044) and a SMRT Cell 8Pac. In all sequencing runs, 2×45 min movies were captured for each SMRT Cell loaded with a single binding complex.

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